While trying to stop Sector 21 escapee Hive from turning the world into mindless zombies, Aaron Stone unknowingly transports African Zombie Weevil bugs containing Hive's mind controlling venom back to Eastland. The weevils hitch a ride on S.T.A.N. and end up infecting Jason and half of the school. With the toxic venom slowly transforming them into insects, Aaron must get a sample of Hive's venom to Emma so she can engineer an antidote before it's too late.