The UK's leading inventors create ingenious new solutions to every-day problems and build life-changing solutions for people in desperate need. Mum of two Shamreen suffers from a degenerative condition which has left her with very limited vision, and she is struggling to get around in public with her two young sons. Seven-year-old Rosie had brain surgery as a baby and now wears a cumbersome medical helmet. She desperately wants the team to invent her a new helmet that will be less visible and help her fit in with her friends. And the team are challenged with coming up with a solution to help two teenage brothers with cystic fibrosis - a debilitating disease that severely affects their breathing.