You, Me & Them tells the story of Lauren and Ed who are madly in love, despite their 26-year age gap. The only problem is that Lauren's family and everyone around them seems to have an opinion on the subject. Ed's ex-wife Lydia rents the house next door to the couple, Lauren's family are constantly meddling and Ed's friends think she's a trophy girlfriend. Characters include Lauren's disapproving parents Emma and Clive; plus her sister Debs, who lives nearby with husband Keith and their two children Ellie and Charlie. Lauren and Ed share their home with Ed's loveably hapless brother Alan whilst Ed's chancer grandson Tim never seems to be too far from his grandfather and his grandfather's wallet. You can choose your partner but you can't choose your family.