After arriving in 1621, Underdog and Sweet Polly meet the pilgrims, and Underdog proves that they're friendly when he does favors for them. Meanwhile, Simon poses as an Indian medicine man and tricks the Indians into thinking that the pilgrims are attacking them, having Cad fire weapons from behind a tree. After both the Indians' reservation and the pilgrims' settlement are destroyed, Simon and Cad return to the 20th century where the Thanksgiving Day Parade and all the remnants of Thanksgiving are gone. With this interference out of the way, Simon gives his army the signal and the villain's armed forces begin their assault on the city. In the past, Underdog and Polly try to stop the war between the Indians and the Pilgrims, but neither side is willing to stop fighting and apologize.