When a plane crashes in Philadelphia due to a gunman opening fire while aloft, the entire team of Megan, Kate, Tommy, Adam, Curtis, Ethan, Riley and Stafford must go into disaster mode. Since the crash hits the city's main power grid, Megan must conduct autopsies on the victims during frequent blackouts, but then one of the bodies goes missing. Meanwhile, Tommy and Riley are in a serious car accident while trying to investigate.