E. G. Daily

Tommy Pickles (voice)

Kath Soucie

Phil DeVille / Lil DeVille (voice)

Cheryl Chase

Angelica Pickles (voice)

Dionne Quan

Kimi Finster (voice)

Tara Strong

Dil Pickles (voice)

Joe Alaskey

Grandpa Lou Pickles (voice)

Melanie Chartoff

Didi Pickles (voice)

Jack Riley

Stu Pickles (voice)

Cree Summer

Susie Carmichael (voice)