A tragic accident brings Frank's ex-wife into the ED as his worst nightmare confronts him. The ED staff is stunned to learn that Frank has a daughter. As Mac faces the possibility of life in a wheelchair, Gill and Cate try to come to terms with it. Jack comes to an uneasy truce with Charlotte and his impending fatherhood, while Dan helps two young girls at the nightclub before they face the disastrous consequences of their choices.