Tracey Ullman

Louise "Little Lulu" Moppet (voice)

Bruce Dinsmore

Thomas "Tubby" Tompkins (voice)

Michael Caloz

Annie Inch (voice)

Dawn Ford

Iggy Inch (voice)

Jacob Tierney

Wilbur Van Snobbe (voice)

Pauline Little

Mrs. Martha Moppet (voice)

Ajay Fry

Alvin Jones

Susan Glover

Mrs. Ellie Tompkins (voice)

Terrence Scammell

Mr. Jim Tompkins / Officer McNabb (voice)

Michael Yarmush

Butch, the Lead West Side Boy (voice)